GLP-1 medications A–Z

Brand and generic names, approved uses and how each medicine is taken, checked against FDA prescribing information and NIDDK. Same ingredient does not mean same approval: several pairs share an active ingredient but are approved for different uses.

Last updated: October 20, 2026

At a glance

BrandGenericFormApproved for weight management?
FoundayoorforglipronPillYes
MounjarotirzepatideInjectionNo (type 2 diabetes)
OzempicsemaglutideInjectionNo (type 2 diabetes)
Rybelsussemaglutide (oral)PillNo (type 2 diabetes)
Saxenda (and generic liraglutide)liraglutideInjectionYes
TrulicitydulaglutideInjectionNo (type 2 diabetes)
VictozaliraglutideInjectionNo (type 2 diabetes)
Wegovy (injection, including Wegovy HD)semaglutideInjectionYes
Wegovy pillsemaglutide (oral, 25 mg)PillYes
ZepboundtirzepatideInjectionYes

Compounded semaglutide and tirzepatide are not on this list because they are not FDA-approved. The FDA says compounded drugs are not reviewed for safety, effectiveness or quality. See which GLP-1s are FDA-approved for weight loss.

Approved for chronic weight management

Foundayo

Generic name: orforglipron

How it's taken
Tablet, once daily, with or without food
FDA-approved for
Chronic weight management in adults with obesity, or overweight plus at least one weight-related condition, with a reduced-calorie diet and more physical activity.
Good to know
FDA-approved April 2026. A small-molecule (non-peptide) GLP-1 receptor agonist that can be taken any time of day without food or water restrictions. Carries the same thyroid C-cell tumor warning as other GLP-1s.

Read more: Which GLP-1 Medications Are FDA-Approved for Weight Loss? (2026 Guide) · GLP-1 Pills vs Injections: How Do They Compare?

Saxenda (and generic liraglutide)

Generic name: liraglutide

How it's taken
Injection, once daily
FDA-approved for
Chronic weight management in adults and in children 12 and older with obesity.
Good to know
The same drug at a lower dose is sold as Victoza for type 2 diabetes. Average weight loss in trials has been smaller than with semaglutide or tirzepatide.

Read more: Which GLP-1 Medications Are FDA-Approved for Weight Loss? (2026 Guide) · GLP-1s and Gallbladder Problems: Gallstones, Risks and Warning Signs

Wegovy (injection, including Wegovy HD)

Generic name: semaglutide

How it's taken
Injection, once weekly; Wegovy HD is a higher-strength 7.2 mg option
FDA-approved for
Chronic weight management in adults and in children 12 and older; lowering the risk of heart attack, stroke and cardiovascular death in adults with heart disease and obesity or overweight; and adults with MASH, a serious fatty liver disease, with moderate to advanced liver scarring.
Good to know
Same active ingredient as Ozempic and Rybelsus, which are diabetes products. Never use two semaglutide products together.

Read more: What Is Semaglutide? · Wegovy vs Ozempic: Same Drug, Different Uses · Semaglutide Cost Without Insurance (2026 Cash Prices Explained)

Wegovy pill

Generic name: semaglutide (oral, 25 mg)

How it's taken
Tablet, once daily in the morning on an empty stomach with up to 4 ounces of plain water, then a 30-minute wait before eating, drinking or other oral medicines
FDA-approved for
Chronic weight management in adults; also labeled for heart-risk reduction.
Good to know
FDA-approved December 22, 2025. Not interchangeable with Rybelsus, a separate oral semaglutide for type 2 diabetes.

Read more: Oral Semaglutide Explained: How the GLP-1 Pill Works · GLP-1 Pills vs Injections: How Do They Compare?

Zepbound

Generic name: tirzepatide

How it's taken
Injection, once weekly (single-dose pens or vials)
FDA-approved for
Weight reduction and long-term weight maintenance in adults with obesity, or overweight plus a weight-related condition; and moderate to severe obstructive sleep apnea in adults with obesity.
Good to know
A dual GIP/GLP-1 receptor agonist. Same active ingredient as Mounjaro, which is a diabetes product. Never use the two together.

Read more: What Is Tirzepatide? · Zepbound vs Mounjaro: What's the Difference?

Approved for type 2 diabetes (not weight management)

Mounjaro

Generic name: tirzepatide

How it's taken
Injection, once weekly
FDA-approved for
Blood sugar control in adults and children 10 and older with type 2 diabetes, and lowering cardiovascular risk in adults with type 2 diabetes at high risk. Not approved for weight management.

Read more: Zepbound vs Mounjaro: What's the Difference? · What Is Tirzepatide?

Ozempic

Generic name: semaglutide

How it's taken
Injection, once weekly (up to 2 mg)
FDA-approved for
Adults with type 2 diabetes: blood sugar control, plus heart and kidney risk reduction in certain patients. Using it only for weight loss is off-label.

Read more: Wegovy vs Ozempic: Same Drug, Different Uses · What Is Semaglutide?

Other FDA-approved weight-management medicines (not GLP-1s)

NIDDK lists these older or specialized medicines alongside the GLP-1s. They work in different ways.

BrandGenericFormApproved for
Contravenaltrexone-bupropionTablet, 1 to 2 times a dayAdults
ImcivreesetmelanotideInjection, once dailyPeople 6 and older with obesity due to one of four rare genetic conditions confirmed by genetic testing
Qsymiaphentermine-topiramatePill, once dailyAdults and children 12 and older
Xenical (Alli, lower dose without prescription)orlistatPill, 3 times a dayAdults and children 12 and older

Important safety notes

  • The GLP-1 medicines above carry a boxed warning about thyroid C-cell tumors and are not for people with a personal or family history of medullary thyroid carcinoma or MEN 2.
  • NIDDK advises against weight-management medicines during pregnancy or when planning a pregnancy.
  • Two products with the same active ingredient (for example Wegovy and Ozempic, or Zepbound and Mounjaro) should never be used together.
  • Which medicine, if any, is right for you is a decision for you and a licensed clinician. See who qualifies and the glossary for terms.

Sources

  1. NIDDK (NIH): Prescription Medications to Treat Overweight & Obesity
  2. FDA label: WEGOVY (semaglutide) injection and tablets, prescribing information (revised 06/2026)
  3. FDA label: ZEPBOUND (tirzepatide) injection, prescribing information (revised 08/2026)
  4. FDA label: FOUNDAYO (orforglipron) tablets, prescribing information (revised 07/2026)
  5. FDA label: OZEMPIC (semaglutide) injection, prescribing information
  6. FDA label: MOUNJARO (tirzepatide) injection, prescribing information (revised 08/2026)
  7. FDA label: RYBELSUS (semaglutide) tablets, prescribing information
  8. DailyMed: SAXENDA (liraglutide) prescribing information
  9. FDA: Approves treatment for serious liver disease known as MASH (Wegovy)
  10. FDA: Approves first medication for obstructive sleep apnea (Zepbound), December 20, 2024
  11. FDA: Concerns with unapproved GLP-1 drugs used for weight loss

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